Course: Principles of human genetics

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Course title Principles of human genetics
Course code KAZ/BPZAG
Organizational form of instruction Lecture
Level of course Bachelor
Year of study not specified
Semester Winter
Number of ECTS credits 2
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
  • Vávrová Helena, MUDr.
Course content
Introduction to genetics Mendel?s laws material essence of genetic information human chromosomes (sex-chromatin) basic genetic terminology interaction of alleles monofactorial inheritance polyfactorial inheritance autosomal and gonosomal inheritance heredity of blood groups heredity of gender examination of human chromosomes mutations and chromosomal aberrations mutagenic factors human genetics methods (biometric statistical methods, studies of twins, genealogy studies) population genetics and prevention of diseases with genetic component (preconceptional care, prenatal care, postnatal care).

Learning activities and teaching methods
Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming)
  • Attendace - 13 hours per semester
  • Preparation for the Exam - 50 hours per semester
Learning outcomes
The discipline results from the recapitulation of knowledge of general genetics gained at secondary school level, which is further expanded with selective additional information on human genetics. The subject includes the following topics: a subject of genetics study, Mendel's laws, basic genetics terms, mutual relations of alleles, monofactorial heredity, polyfactorial heredity, autosomal and gonosomal heredity, human chromosomes (se-chromatin), corporeity of genetic information, heredity of blood groups, heredity of gender, examination of human chromosomes, mutations and chromosomal aberrations, mutagenous factors, human genetics methods (biometric statistical methods, twins study, genealogy study), genetics of populations and the prevention of diseases with a genetic factor (preconception care, prenatal care, postnatal care).
After completing the course, students should be able to: - Explain the mechanisms of heredity and variation in the human population - Describe the nature of biological inheritance - Be able to explain the types of inheritance, concepts concerning the relationship of alleles - To characterize the nature of inheritance of sex and blood groups - Calculate the frequency of heterozygotes in the population of a particular character - To understand the preventive possibilities of human genetics - Outline the ethical issues in human genetics
Basic knowledge of cell biology.

Assessment methods and criteria
Mark, Oral exam

Ability to work with data and printed literary sources, online connectivity.
Recommended literature
  • Kočárek, E. (2004). Genetika. Praha - Scientia.
  • Machová, J. (2002). Biologie člověka pro učitele. Praha.
  • Otová a kol. (1997). Biologie člověka pro bakalářské studium na lékařských fakultách .I. Základy genetoky, II. Vývoj a růst člověka.. Karolinum Praha.

Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester
Faculty of Education Social health work with focus on education (BB15) Pedagogy, teacher training and social care 1 Winter