Course: Molecular Biophysics

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Course title Molecular Biophysics
Course code KBF/PGSMB
Organizational form of instruction Lecture
Level of course Doctoral
Year of study not specified
Semester Winter and summer
Number of ECTS credits 20
Language of instruction Czech, English
Status of course unspecified
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Kašpárková Jana, prof. RNDr. Ph.D.
Course content
Origin and evolution of life. Cell, cellular organelle. Biological membranes - basic function a structure. Physical properties of biological membranes. Organization of membrane lipids. Phase transitions. Mobility of membrane components. Membrane transport . Basis characteristics of major transport mechanisms. Diffusion. Transfer of ions across membrane. Mediated diffusion (carriers, channels). Active transport. Secondary active transport. Reception and processing of information by membranes. Physical signals. External chemical signals. Molecules of cell surface. Cellular recognition.Receptors, receptor response. Endocytosis mediated by receptors. Cellular adhesion. Cell dynamics: Cytoskeleton. Cellular contacts. Molecular motors. Active motion. Composition and structure of chromosomes. Gene manipulations, recombinant DNA technology.

Learning activities and teaching methods
Lecture, Work with Text (with Book, Textbook)
  • Homework for Teaching - 10 hours per semester
  • Preparation for the Exam - 80 hours per semester
Learning outcomes
Cell, cellular organelles. Membrane transport, receptors. Cellular dynamics.
Evaluation Evaluate the particular methods and principles, explain the aspects and results concerning the given issue, integrate the knowledge, predict the solutions, evaluate the results and outcomes.
Prerequisites
Knowledge of biochemistry, molecular biophysics and molecular biology.

Assessment methods and criteria
Oral exam

Knowledge within the scope of the course topics (examination)
Recommended literature
  • Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P., Wilson, J., & Hunt, T. (2008). Molecular biology of the cell. New York, N.Y: Garland Science.
  • Bergethon, P. R. (1998). The physical basis of biochemistry: the foundations of molecular biophysics. New York: Springer.
  • Creighton, T. E. (2010). The physical and chemical basis of molecular biology. [Great Britain]: Helvetian Press.
  • Tuszynski, J. A., & Kurzynski, M. (2003). Introduction to molecular biophysics. Boca Raton: CRC Press.


Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester