Course: Introduction to Biological Chemistry

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Course title Introduction to Biological Chemistry
Course code KBF/UBCH
Organizational form of instruction Lecture
Level of course Master
Year of study not specified
Semester Winter
Number of ECTS credits 5
Language of instruction Czech
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
  • Nauš Jan, prof. RNDr. CSc.
Course content
1) Basic concepts in chemistry. 2) Electronic structure of atoms, ionization energy and electronic affinity. Electronegativity of atoms. Oxidation number of atoms. Periodic table of atoms. Nomenclature of anorganic compounds, ions, oxides and oxoacids. 3) Chemical bond. Covalent, ion, metal and hydrogen bond. Van der Waals and coordination bond, hydrophobic and stacking interaction. Chemical and physical ways of bond description. Theory of resonance strunctures. 4) Elements and their significance in living nature and for a man. Biogenic and abiogenic elements. 5) Organic compounds. Classification of organic compounds, their physical and chemical properties. Basics of nomenclature of the organic compounds. Hydrocarbons, derivatives of hydrocarbons. Herterocyclic compounds. 6) Structure of organic compounds. Hybridization of atomic orbitals. 7) Chemical reactions and chemical equations. 8) Reactions of organic compounds. 9) Organometallic, organosiliceous and coordination compounds. Polymers, medicaments, selected natural compounds.

Learning activities and teaching methods
  • Homework for Teaching - 20 hours per semester
  • Preparation for the Exam - 40 hours per semester
  • Attendace - 42 hours per semester
Learning outcomes
The goal of this course is to repeat and deepen the basic chemical concepts and formulas for students of biophysics as a basis for the study of biochemistry and molecular biology. The basic chemical and physical characteristics of atoms and molecules are explained together with chemical bonds and interactions, elements and their significance in living nature. Presented are also the basic groups of organic compounds, the structure of organic molecules and chemical reactions. The chemical description is compared with the physical approach.
Knowledge Define the main ideas and conceptions of the subject, describe the main approaches of the studied topics, recall the theoretical knowledge for solution of model problems.
Basic knowledge of physics, chemistry and biology.

Assessment methods and criteria

Understanding of the nature of the chemical approach to problems, acquiring of the basics of chemical disciplins. Knowledge of basic chemical compounds.
Recommended literature
  • Hrnčiar P. (1990). Organická chémia. SPN Bratislava.
  • Nováček F. (1986). Fytochemické základy botaniky. UP Olomouc.
  • Orchin M. a kol. (1986). Organická chemie. Příruční naučný slovník.. SNTL Praha.
  • Pacák J. (1997). Jak rozumět organické chemii. Karolinum Praha.
  • Panico R., Powell W.H., Richer J.-C. (2000). Průvodce názvoslovím organických sloučenin podle IUPAC. Academia Praha.

Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester