Course: Clinical Biophysics

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Course title Clinical Biophysics
Course code LBF/VA021
Organizational form of instruction Lecture + Seminar
Level of course Master
Year of study not specified
Semester Winter
Number of ECTS credits 2
Language of instruction English
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Course availability The course is available to visiting students
  • Doležal Ladislav, Ing. CSc.
  • Bajgar Robert, MUDr. Mgr. Ph.D.
  • Maceček Jaroslav, Mgr. Ph.D.
  • Kolářová Hana, prof. RNDr. CSc.
  • Binder Svatopluk, Mgr. Ph.D.
  • Bartoň Tománková Kateřina, doc. Ing. Ph.D.
Course content
Lasers in medicine, microsurgery. Scanning methods for body temperature measurement. Radiation risks and safety. Stochastic and deterministic effects. X-ray diagnostic methods I. Skiagraphy, skiascopy, angiography (AG), digital subtraction angiography (DSA). X-ray diagnostic methods II. Computer tomography (CT), CT angiography (CTA). Radionuclide imaging, positron emission tomography (PET). Pulse wave. Clinical applications of ultrasonics. Photodynamic therapy (PDT). Principal of PDT, types of photodynamic active drugs, sources of radiation. Biological response, methods of cell damage analysing, clinical applications. Nuclear magnetic resonance imaging (MRI). Biophysical principles of non-invasive and invasive therapeutic methods. Hemodialysis, peritoneal dialysis, continual methods, hemoperfusion, plasmapheresis. Electrodiagnostic methods. Presentation of seminar papers.

Learning activities and teaching methods
Lecture, Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming)
Learning outcomes
The course offers an overview of modern diagnostic and therapeutic methods such as X-ray diagnostic methods, radionuclide imaging, magnetic resonance imaging, photodynamic therapy, electrodiagnostic methods, ultrasound in medicine and others. Each topic introduces and explains the physical principle of the method and of course its clinical applications. Specially, the emphasis is placed on such methods, which students meet at the clinics of the University Teaching Hospital.
Students will be able to understand the basic physical principles of commonly used diagnostic and therapeutic methods including the data analysis and image processing. They will be able to make right decision and chose adequate instrumental technique to diagnose or treat different kinds of diseases.
Students ought to have fundamental attainments in medical biophysics at a college level.
IN0/VAA11 and MIK/VAA12 and SOL/VAB12 and FAR/VAB11 and IN2/VAB22 and PAT/VAB11 and PFY/VAB11 and PSY/VAB13 and KIM/VAB12 and CJA/VAB43

Assessment methods and criteria
Mark, Written exam, Student performance, Seminar Work

Active participation in seminars
Recommended literature
  • Hrazdira, I., Bourek, A., Mornstein, V. (2000). Biophysical Principles of Medical Technology. Brno: Masaryk University.
  • Nölting, B. (2005). Methods in Modern Biophysics. Springer.

Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester
Faculty of Medicine and Dentistry General Medicine (2014) Medical sciences 4 Winter
Faculty of Medicine and Dentistry General Medicine (2) Medical sciences 4 Winter