Course: Molecular Oncology in Clinical Practice

« Back
Course title Molecular Oncology in Clinical Practice
Course code ONK/VCA31
Organizational form of instruction Lecture + Seminar
Level of course Master
Year of study not specified
Semester Winter and summer
Number of ECTS credits 1
Language of instruction Czech
Status of course Optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Course availability The course is available to visiting students
Lecturer(s)
  • Mohelníková Duchoňová Beatrice, doc. MUDr. Ph.D.
  • Vrána David, doc. MUDr. Ph.D.
  • Hudcová Magdalena, MUDr. Ph.D.
Course content
Familial cancer - diagnosis, outputs for practice The sporadic form of cancer - genetic polymorphisms and the cancer risk Signaling pathways and targeted therapy - understanding the effects, indications, side effects Biomarkers of effect and toxicity in chemotherapy - use of pharmacogenomics in practice:       - Membrane Transporters       - Biotransformation enzymes

Learning activities and teaching methods
Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming)
Learning outcomes
The course "Molecular Oncology in Clinical Practice" will strengthen the interdisciplinary nature of teaching Oncology and the result will be to integrate the latest scientific knowledge of molecular and cellular biology and clinical practice. The aim of the course is to acquaint students with familial forms of cancer, their diagnosis and outcomes for clinical practice, as well as to get acquainted with the problems and possibilities of genetic polymorphisms and how they influence the risk of cancer sunset. The course focuses on the use of pharmacogenomics in clinical practice, provides an overview of important signaling pathways and their possible influence by target therapies, and biomarkers of effect and toxicity of chemotherapy.
Students will be able to use modern knowledge of molecular biology in the care of patients with malignant tumors.
Prerequisites
Passed exam - Biology, Biochemistry, Pathology and Oncology.
ONK/VC011 and LCH/VCA20

Assessment methods and criteria
Student performance

100% active participation in seminars
Recommended literature
  • Gelmann, E.P. et al. (2013). Molecular Oncology. Cambridge University.
  • Klener, P. a kol. (2013). Principy systémové a protinádorové léčby. Praha Grada.


Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester
Faculty of Medicine and Dentistry General Medicine (2012) Medical sciences 5 -
Faculty of Medicine and Dentistry General Medicine (2011) Medical sciences 5 -
Faculty of Medicine and Dentistry General Medicine (2015) Medical sciences 5 -
Faculty of Medicine and Dentistry General Medicine (2014) Medical sciences 5 -